The MR CLEAN-NO IV trial is a Multicenter Randomized CLinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands investigating the added benefit of intravenous alteplase prior to intra-arterial thrombectomy in stroke patients with an intracranial occlusion of the anterior circulation.

MR CLEAN-NO IV is one of the 5 randomized trials that will be conducted by the Collaboration for New Treatments of Acute Stroke (CONTRAST) consortium.

The left hand menu helps you to navigate through this website and access more information about the trial.

Kind regards,

On behalf of the MR CLEAN-NO IV executive committee and the CONTRAST consortium:
Yvo Roos,
Charles Majoie,
MR CLEAN-NO IV principle investigators